Kinetic Assays

“We are experts in the development and application of kinetic assays to measure the association and dissociation rates of unlabelled¬†ligands.”

We have extensive experience of utilizing competition association assays in both radioligand and time-resolved fluorescence resonance energy transfer (TR-FRET) formats

Assays are medium throughput (384 well), capable of performing fragment screening

We have experience on a range of target classes, including GPCRs, enzymes and protein-protein interactions

Watch a recent webinar from Prof Charlton in collaboration with BMG Labtech and Cisbio and on why and how to measure receptor kinetics in drug discovery programs: http://www.ddw-online.com/drug-discovery/p321001-webinar-the-kinetics-of-drug-receptor-binding:-why-it-is-important-and-how-we-can-measure-it.html