Our Resources
The Excellerate team has made significant contributions to analytical pharmacology, particularly in the field of binding and signalling kinetics.
Here you can access useful fact sheets from the team, as well as publications, presentations and other useful content.
Publications
11 January, 2025
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Paper
Micro-pharmacokinetics: Qualifying local drug concentration at live cell membranes.
Karolina Gherbi, Stephen J Briddon, Steven J Charlton
11 January, 2025
Read
Paper
Airway remodeling disease: primary human structural cells and phenotypic and pathway assays to identify targets with potential to prevent or reverse remodeling.
Elizabeth M Rosethorne, Steven J Charlton
11 January, 2025
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Paper
Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D2 receptors.
David A Sykes, Holly Moore, Lisa Stott, Nicholas Holliday, Jonathan A Javitch, J Robert Lane, Steven J Charton
Webinars
11 January, 2025
Watch Webinar
The kinetics of drug binding – Prof Steven Charlton, with BMG Labtech
11 January, 2025
Watch Webinar
Putting the dynamics into compound profiling: using kinetic assays to shape drug discovery (splabtech.com)
Fact sheets
Posters
11 January, 2025
Download
Antagonist binding kinetics at the human D1 dopamine receptor determined by HTRF assay.
Kathy Sengmany, Ka-Wing Wong, Steven J Charlton, Nicholas Holliday. Presented at ELRIG Drug Discovery and the British Pharmacology Society, 2019
